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Mortality curves for guinea pigs with disseminated aspergillosis that were treated from day 0 to day 13 with itraconazole-cyclodextrin given i.v. Open circles, placebo treatment; squares, 1.25 mg/kg b.i.d.; triangles, 2.5 mg/kg b.i.d.; diamonds, 5 mg/kg b.i.d.; filled circles, immunosuppression with mechlorethamine hydrochloride and treatment with i.v. itraconazole at 10 mg/kg b.i.d.
