Table 2.
Studies showing metabolic abnormalities in patients of hidradenitis suppurativa.
| Study | Sample size | Type of study | Investigations/Tools | Results |
|---|---|---|---|---|
| 1. Kamat et al.[11] 2021 | 22 cases | Hospital-based retrospective study | BMI, PCOS | High BMI (45.4%) and obesity (18.1%) patients. Patients undergoing procedural plus pharmacotherapy had a better outcome |
| 2. Offidani et al.[5] 2019 | 8 cases | Case series | Body mass index, serum testosterone, and serum insulin | High BMI in all patients, hyperandrogenism in two patients, precocious puberty and hyperinsulinemia in one patient |
| 3. Lee et al.[3]2018 | 28,516 cases | Population-based cross-sectional study | Blood pressure, blood glucose, triglycerides, total cholesterol, low density and high density and low-density lipoprotein | Significantly higher risk of type 2 diabetes (Odds ratio 1.820), hypertension (OR 1.266) and hyperlipidaemia (OR 1.308) |
| 4. Garg et al.[8] 2018 | 22,990 cases (female) | Population-based study | Weight, blood glucose, markers of PCOS | The significant association between HS and PCOS (9% of females with HS had PCOS when compared to 2.9% of the general population without HS). PCOS was significantly higher among HS patients with diabetes mellitus (17.2%) and obesity (11%) |
| 5. Crowley et al.[6] 2014 | 154 cases | Cross-sectional study | Weight, blood pressure, blood glucose, total cholesterol, triglycerides, low-density and high-density lipoprotein | Morbid obesity in 38.3% of patients (odds ratio 2.01) 39.6% of patients with hypertension, 11.7% with hyperlipidaemia, 6.5% with diabetes mellitus and 35.7% of patients had two cardiovascular risk factors |
| 6. Sabat et al.[7] 2012 | 80 cases and 100 controls | Case-control study | Height, weight, blood pressure, waist circumference, blood glucose, triglycerides and high-density lipoprotein | Metabolic syndrome was seen to be significantly more common in patients with HS (40% cases vs. 13% controls) |
| 7. Canoui-Poitrine et al.[4] 2009 | 302 cases | Case control study | Body mass index, blood pressure, blood glucose, total cholesterol, triglycerides, low-density and high-density lipoprotein | Significantly higher BMI in cases compared to controls |