Skip to main content
. 2023 May 4;7(5):e0055. doi: 10.1097/HC9.0000000000000055

FIGURE 3.

FIGURE 3

Performance of Agile 3+ versus FIB-4 and LSM by vibration-controlled transient elastography in identifying advanced fibrosis. In the rule-out zone, FIB-4 (LB F<3) represents the percentage of patients with a FIB-4 under the rule-out cutoff and with a fibrosis stage <3 (true negative). FIB-4 (LB F≥3) represents the percentage of patients with a FIB-4 under the rule-out cutoff and a fibrosis stage ≥3 (false negative). In the intermediate zone, FIB-4 (LB F<3) represents the percentage of patients with a FIB-4 between the rule-out and the rule-in cutoffs and a fibrosis stage <3. FIB-4 (LB F≥3) represents the percentage of patients with a FIB-4 between the rule-out and the rule-in cutoffs and a fibrosis stage ≥3. In the rule-in zone, FIB-4 (LB F<3) represents the percentage of patients with a FIB-4 above the rule-in cutoff and with a fibrosis stage <3 (false positive). FIB-4 (LB F≥3) represents the percentage of patients with a FIB-4 above the rule-in cutoff and a fibrosis stage ≥3 (true positive). As with FIB-4, the same interpretation applies with LSM (LB F<3), LSM (F≥3), Agile 4 (LB F<3), and Agile (LB F≥3). Advanced fibrosis is defined as ≥fibrosis stage 3. Abbreviations: FIB-4, fibrosis-4 index; LB, liver biopsy; LSM, liver stiffness measurement.