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. 2023 May 4;7(5):e0055. doi: 10.1097/HC9.0000000000000055

FIGURE 5.

FIGURE 5

Performance of Agile 4 versus LSM by vibration-controlled transient elastography in identifying cirrhosis. In the rule-out zone, LSM (LB F<4) represents the percentage of patients with an LSM under the rule-out cutoff and with a fibrosis stage <4 (true negative). LSM (LB F=4) represents the percentage of patients with an LSM under the rule-out cutoff and a fibrosis stage = 4 (false negative). In the intermediate zone, LSM (LB F<4) represents the percentage of patients with an LSM between the rule-out and the rule-in cutoffs and a fibrosis stage <4. LSM (LB F=4) represents the percentage of patients with an LSM between the rule-out and the rule-in cutoffs and a fibrosis stage = 4. In the rule-in zone, LSM (LB F<4) represents the percentage of patients with an LSM above the rule-in cutoff and with a fibrosis stage <4 (false positive). LSM (LB F=4) represents the percentage of patients with an LSM above the rule-in cutoff and a fibrosis stage = 4 (true positive). As with LSM, the same interpretation applies with Agile 4 (LB F<4) and Agile (LB F=4). Cirrhosis is defined as fibrosis stage 4. Abbreviations: LB, liver biopsy; LSM, liver stiffness measurement.