Skip to main content
. 2023 May 4;7(5):e0055. doi: 10.1097/HC9.0000000000000055

TABLE 1.

Demographic characteristics of study cohort overall, with obesity, and with diabetes

Median (IQR) Overall Patients with obesity Patients with diabetes
Demographics
 Age (y) n=548 n=359 n=292
58 (15) 57 (15) 59 (14)
 Male sex, N/n (%) 190/548 (35) 124/359 (35) 100/292 (34)
 BMI (kg/m²) n=501 n=359 n=267
33.3 (8.5) 35.7 (7.5) 33.3 (8.1)
Comorbidities, N/n (%)
 Diabetes 292/548 (53) 199/359 (55) 292/292 (100)
 Hypertension 283/547 (52) 193/359 (54) 176/292 (60)
 Obesity 359/501 (72) 359/359 (100) 199/267 (75)
 Morbid obesity 99/501 (20) 99/359 (28) 53/267 (20)
Blood
 AST (IU/L) n=548 n=359 n=292
36 (30) 40 (31) 35 (28)
 ALT (IU/L) n=548 n=359 n=292
44 (42) 45 (46.5) 41 (39)
 AST/ALT n=548 n=359 n=292
0.9 (0.4) 0.8 (0.4) 0.9 (0.4)
 Platelets (1000/uL) n=548 n=359 n=292
208 (111) 214 (112) 204 (102)
 HDL (mmol/L) n=413 n=264 n=292
1.2 (0.4) 1.2 (0.4) 1.1 (0.4)
 LDL (mmol/L) n=401 n=255 n=209
2.5 (1.2) 2.5 (1.2) 2.4 (1.2)
 Albumin (g/L) n=534 n=353 n=287
44 (4) 43 (4) 44 (5)
 Bilirubin (µmol/L) n=547 n=358 n=292
10.3 (6.8) 9.3 (5.1) 10.3 (6.8)
 Alkaline phosphatase (IU/L) n=405 n=272 n=223
81 (36) 82 (37) 81 (38)
Noninvasive tests
 FIB-4 n=548 n=359 n=292
1.67 (1.61) 1.7 (1.5) 1.7 (1.5)
 LSM by VCTE (kPa) n=548 n=359 n=292
12 (10) 13 (10) 12 (10)
Fibrosis, N/n (%)
 NASH 239/477 (50) 167/310 (54) 133/252 (53)
Fibrosis stage by Kleiner, N/n (%)
 F0 75/548 (14) 46/359 (13) 35/292 (12)
 F1 114/548 (21) 73/359 (20) 49/292 (17)
 F2 104/548 (19) 75/359 (21) 61/292 (21)
 F3 111/548 (20) 70/359 (20) 72/292 (25)
 F4 144/548 (26) 95/359 (27) 75/292 (26)

Note: Obesity is defined as BMI ≥30. Morbid obesity is defined as BMI ≥35.

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; F0, fibrosis stage 0; F1, fibrosis stage 1; F2, fibrosis stage 2; F3, fibrosis stage 3; F4, fibrosis stage 4; FIB-4, fibrosis-4 index; IQR, interquartile range; LSM, liver stiffness measurement; VCTE, vibration-controlled transient elastography.