TABLE 1.
Fluoroquinolone susceptibilities of the ATCC strain and clinical isolate of S. pyogenes determined by disk diffusion and Etest
| Quinolone | Result for straina:
|
|||
|---|---|---|---|---|
| ATCC 700294
|
NIH-R01-GAS
|
|||
| KB disk (mm) | Etest (μg/ml) | KB disk (mm) | Etest (μg/ml) | |
| Ciprofloxacin | 21 | 0.50 | No zone | >32 |
| Clinafloxacin | 23 | 0.10 | 19 | 1.00 |
| Enrofloxacin | 13 | ND | No zone | ND |
| Grepafloxacin | 21 | 0.50 | No zone | >32 |
| Levofloxacin | 20 | 0.50 | No zone | >32 |
| Lomefloxacin | 16 | ND | No zone | ND |
| Norfloxacin | 20 | 3.00 | No zone | >256 |
| Ofloxacin | 18 | ND | No zone | ND |
| Sparfloxacin | 21 | 0.50 | No zone | >32 |
| Trovafloxacin | 21 | 0.13 | No zone | >32 |
a
Results for disk diffusion are expressed as diameters of zones of inhibition. Results for Etest are expressed as MICs of quinolones. ND, not determined.