TABLE 1.
Treatment | Animal | Virus recovery at wk postchallengea
|
No. of animals protected/total | |||
---|---|---|---|---|---|---|
2 | 4 | 8 | 12b | |||
CAP:I | 89D420 | 0 | 0 | 0 | 0 [+] | 1/6 |
H608 | 0 | 0 | 0 | 0 [+] | ||
359L | + | + | + | ND | ||
407L | 0 | 0 | 0 | 0 [−] | ||
H671 | + | + | + | ND | ||
89D367 | + | + | + | ND | ||
CAP:II | 89C001 | 0 | 0 | 0 | 0 [−] | 4/6 |
P778 | 0 | 0 | 0 | 0 [−] | ||
976W | ++ | ++ | ++ | ND | ||
P851 | ++ | ++ | ++ | ND | ||
936P | 0 | 0 | 0 | 0 [−] | ||
P407 | 0 | 0 | 0 | 0 [−] | ||
Control | 89D264 | ++ | ++ | ++ | ++ | 0/4 |
89D205 | + | + | + | + | ||
59R | ++ | ++ | ++ | ++ | ||
AH37 | ++ | ++ | ++ | ++ |
+, Positive results after single treatment and challenge; ++, positive results after double treatment and challenge; ND, not done; 0, negative result.
Symbols in brackets indicate presence (+) or absence (−) of proviral DNA 12 weeks after double treatment and challenge for animals negative for virus isolation.