TABLE 2.
Treatment | Animal | Absorbance at 405 nm at wk postchallenge
|
No. of antibody-negative animals/total | |||
---|---|---|---|---|---|---|
2 | 4 | 8 | 12 | |||
CAP:I | 89D420 | 0.182 | 0.221 | 0.169 | 0.034 | 3/6 |
H608 | 0.171 | 0.141 | 0.151 | 0.035 | ||
359L | 0.167 | 0.455 | ND | ND | ||
407L | 0.157 | 0.156 | 0.160 | 0.043 | ||
H671 | 0.170 | 0.426 | ND | ND | ||
89D367 | 0.170 | 0.304 | ND | ND | ||
CAP:II | 89C001 | 0.168 | 0.055 | 0.048 | 0.039 | 4/6 |
P778 | 0.181 | 0.089 | 0.013 | 0.035 | ||
976W | 0.188 | 0.236 | 1.913 | 1.486 | ||
P851 | 0.193 | 0.167 | 0.377 | 0.172 | ||
936P | 0.193 | 0.035 | 0.036 | 0.040 | ||
P407 | 0.158 | 0.066 | 0.087 | 0.053 | ||
Control | 89D264 | 0.159 | 0.371 | 0.853 | 0.595 | 0/4 |
89D205 | 0.175 | 0.466 | ND | ND | ||
59R | 0.156 | 0.495 | 1.069 | 0.347 | ||
AH37 | 0.159 | 0.452 | 0.765 | 0.467 |
Results in italics correspond to single treatment and challenge. A whole-virus antigen ELISA was used to evaluate seroconversion to SIV. The historical cutoff for this assay is an optical density of 0.250. ND, not done. Positive responses are indicated in bold.