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. Author manuscript; available in PMC: 2023 May 6.
Published in final edited form as: Biochemistry. 2022 Sep 26;61(20):2182–2187. doi: 10.1021/acs.biochem.2c00472

Figure 1.

Figure 1.

The catalytic cycle for nicotine oxidoreductase (NicA2). Like many flavin-dependent enzymes, the catalytic cycle can be split into reductive and oxidative half-reactions that can be studied independently.