Table 3.

Mortality and risk analysis in patients with pleural infection cases

Characteristic	Pleural Infection
	Total patients (N=100)	30-day mortality N (%)	90-day mortality N (%)	365-day mortality N (%)
(A) Mortality among 100 pneumococcal pleural infection cases with different clinical features and RAPID severity scores
Disease characteristics
Pus	59	0 (0)	0 (0)	1 (2)
No pus	41	9 (22)	12 (29)	12 (29)
Loculation present	49	8 (16)	10 (20)	12 (25)
No loculation detected	51	1 (2)	2 (4)	5 (10)
Fibrinolytics used	33	4 (12)	6 (18)	11 (33)
Surgical management*	29	0 (0)	0 (0)	0 (0)
Loculation present	23	0 (0)	0 (0)	0 (0)
No loculation	6	0 (0)	0 (0)	0 (0)
No surgical management	71	9 (13)	12 (17)	17 (24)
RAPID risk group
Low	36	1 (3)	1 (3)	3 (8)
Medium	46	2 (4)	3 (7)	4 (9)
High	18	6 (33)	10 (55)	13 (72)

(B) Cox regression analysis for risk factors in patients with pleural infection
Analysis	Factor		Beta (β) estimate	HR	95% CI	Р value
30-day mortality	RAPID group	Low	–	–	–	–
		Medium	13.52	12.04	0.23 to 39.87	0.674
		High	28.51	19.33	0.55 to 92.33	0.638
	Age		−0.002	0.998	0.96 to 1.05	0.921
	Loculation		1.705	5.502	0.99 to 103	0.111
90-day mortality	RAPID group	Low	–	–	–	–
		Medium	0.573	1.773	0.19 to 38.77	0.642
		High	2.709	15.01	1.24 to 40.06	0.049
	Age		0.015	1.02	0.97 to 1.07	0.55
	Loculation		1.582	4.86	1.27 to 31.87	0.043
365-day mortality	RAPID group age	Low	–	–	–	–
		Medium	0.573	1.773	0.19 to 38.77	0.642
		High	2.709	15.01	1.24 to 40.06	0.049
	Age		0.027	1.028	0.99 to 1.07	0.188
	Loculation		1.041	2.836	1.04 to 9.00	0.05

RAPID (Renal, Age, Purulence, Infection source, and Dietary factors) score 0–2 represents low risk, 3–4 medium risk and 5–7 high risk.

Proportional hazard assumptions were tested by visual assessment of the Kaplan-Meier survival curve, log(-log) plots and Schoenfeld Residuals (online supplemental data 8).

*Eighteen patients underwent surgery after fibrinolytic usage.