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. 2023 May 3;13(5):e072110. doi: 10.1136/bmjopen-2023-072110

Table 2.

Adjusted HRs for all-cause and cardiovascular mortality

All cause CVD
All CVD IHD CeVD
Women, n 381 153 63 33
 Age at mortality, years, median (IQR) 81 (76, 86) 83 (79, 87) 83 (79, 87) 82 (77, 87)
 Time to mortality*, years, median (IQR) 11 (8, 14) 11 (8, 14) 11 (7, 15) 11 (7, 14)
Adjusted HR (95% CI)†
 SUA <360 µmol/L 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
 SUA 360–419 µmol/L 1.03 (0.78 to 1.35) 0.79 (0.50 to 1.25) 1.37 (0.72 to 2.61) 0.25 (0.06 to 1.08)
 SUA ≥420 µmol/L 1.32 (1.01 to 1.74) 1.31 (0.87 to 1.99) 1.96 (1.05 to 3.65) 0.82 (0.30 to 2.22)
P for trend 0.045 0.56 0.039 0.17
Men, n 506 221 138 33
 Age at mortality, years, median (IQR) 80 (74, 84) 80 (76, 85) 79 (74, 84) 82 (79, 87)
 Time to mortality*, years, median (IQR) 10 (6, 14) 10 (7, 14) 11 (6, 13) 10 (7, 14)
Adjusted HR (95% CI)†
 SUA <360 µmol/L 1.00 (Reference) 1.00 (Reference) 1.00 (Reference) 1.00 (Reference)
 SUA 360–419 µmol/L 1.11 (0.89 to 1.39) 1.18 (0.83 to 1.67) 1.23 (0.79 to 1.91) 1.53 (0.65 to 3.60)
 SUA ≥420 µmol/L 1.29 (1.05 to 1.60) 1.41 (1.01 to 1.95) 1.49 (0.99 to 2.45) 1.12 (0.47 to 2.66)
P for trend 0.018 0.040 0.042 0.97

*Time from enrolment in the study to death.

†Adjusted for age, gender, education, smoking status, body mass index (BMI), hypertension and dyslipidaemia.

CeVD, cerebrovascular disease; CVD, cardiovascular disease; IHD, ischaemic heart disease; SUA, serum uric acid.