Characteristic Study ID	Intervention and comparator	Sex [female %]	Age [mean years (SD)/range]	TC [mean mmol/L (SD)]	BMI [mean kg/m2 (SD)]	Co‐medications / Co‐interventions	Co‐morbidities
Aubertin‐Leheudre 2008	Isoflavones (70 mg)	100	50‐70	5.90 (0.59)	31.2 (4.5)	‐	‐
	Placebo	100	50‐70	6.02 (0.90)	32.8 (4.8)
Dewell 2002	Isoflavones (150 mg)	100	69 (4) 64‐83	6.8 (0.9)	25 (4)	1 participant took simvastatin and 1 took fluvastatin	‐
	Maltodextrin with 10% caramel	100	70 (4) 65‐77	6.3 (2.0)	25 (4)
Gardner 2001	Isoflavones (80 mg)	100	62.6 (7.3)	6.1 (0.6)	25.6 (4.4)	‐	‐
	Trace amounts of isoflavones	100	58.4 (7.2)	6.2 (0.9)	25.4 (3.6)
Mackey 2000	Isoflavones (65 mg)	100	56.4 (4.9)	7.29 (0.90)	‐	‐	‐
	Less than 4 mg isoflavones	100	56.8 (4.2)	7.47 (1.04)
Wang 2005	Isoflavones (158 mg)	100	45‐55	7.63 (0.18)	‐	‐	‐
	Placebo	100	45‐55	7.74 (0.23)
Footnotes "‐" denotes not reported. BMI: body mass index; SD: standard deviation; TC: total cholesterol.