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. 2023 May 2;19:1069–1084. doi: 10.2147/NDT.S405728

Table 6.

Adverse Effects of Acupuncture for MDD in the Intervention Group Compared to the Control Group

Adverse Effects Intervention Group Control Group
Frequency Proportion (%) Frequency Proportion (%)
Behavioral Toxicity Excitement or arousal 1 0.15 5 0.73
Decreased activity 2 0.29 4 0.58
Insomnia 21 3.07 38 5.55
Sleepiness 9 1.31 21 3.07
Nervous System Tremor 3 0.44 11 1.61
Restlessness 0 0.00 3 0.44
Dizziness and headache 38 5.55 55 8.03
Dry mouth 34 4.96 49 7.15
Vegetative Nervous System Blurred vision 4 0.58 11 1.61
Constipation 23 3.36 39 5.69
Sweating 1 0.15 7 1.02
Nausea and vomiting 29 4.23 52 7.59
Diarrhea 9 1.31 12 1.75
Cardiovascular System Lower blood pressure 4 0.58 9 1.31
Heartburn and palpitations 6 0.88 22 3.21
High blood pressure 2 0.29 1 0.15
Electrocardiogram abnormalities 4 0.58 5 0.73
Heart attack 1 0.15 0 0.00
Other Itchy skin or rash 3 0.44 10 1.46
Weight gain 5 0.73 5 0.73
Loss of appetite or anorexia 22 3.21 37 5.40
Abnormal liver function 2 0.29 3 0.44
Difficulty in urination 5 0.73 7 1.02
Anxiety 2 0.29 5 0.73
Fatigue 6 0.88 8 1.17
Sexual dysfunction 2 0.29 8 1.17
Chest tightness 1 0.15 2 0.29
Menstrual disorders 1 0.15 1 0.15
Mild burns 2 0.29 0 0.00
Acupuncture pain 3 0.44 0 0.00
Subcutaneous hematoma 3 0.44 0 0.00
Acupuncture dizziness 6 0.88 0 0.00
Hospitalization after external stimulation 1 0.15 0 0.00