Table 1.
Patient and disease characteristics at time of nephroureterectomy, separately for those patients with variant histology on pathology and those without any variant histology. Results are presented as median (quartiles) and frequency (%). Groups are compared by Wilcoxon, χ2 or Fisher’s exact test.
| Characteristic | No Variant Histology, n = 658 | Variant Histology, n = 47 | p-value |
|---|---|---|---|
|
| |||
| Age at surgery (yr) | 71 (64, 77) | 70 (63, 78) | 0.9 |
| Surgical approach | 0.2 | ||
| Laparoscopic | 71 (11) | 1 (2) | |
| Open | 446 (68) | 35 (74) | |
| Robotic | 141 (21) | 11 (23) | |
| Year of surgery | 2009 (2003, 2015) | 2013 (2010, 2016) | 0.003 |
| Bilateral nephroureterectomy | 1 (0) | 0 (0) | >0.9 |
| Neoadjuvant chemotherapy | 97 (15) | 18 (38) | <0.001 |
| Pathologic T stage | <0.001 | ||
| pTA/IS/1 | 365 (55) | 3 (6) | |
| pT2 | 112 (17) | 11 (23) | |
| pT3 | 168 (26) | 28 (60) | |
| pT4 | 13 (2) | 5 (11) | |
| Lymph node dissection | 475 (72) | 38 (81) | 0.2 |
| Pathologic N stage among those who underwent a lymph node dissection | 0.2 | ||
| pN0 | 391 (82) | 28 (74) | |
| pN1–3 | 84 (18) | 10 (26) | |
| Number of nodes removed among those who underwent a lymph node dissection | 9 (4, 17) | 13 (6, 18) | 0.2 |
| Unknown | 1 | 0 | |