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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Free Radic Biol Med. 2023 Mar 2;200:59–72. doi: 10.1016/j.freeradbiomed.2023.02.021

Fig. 5. Effects of tempol in the regulation of blood pressure and sodium excretion in selenium-deficient rats.

Fig. 5.

Fig. 5.

After feeding the indicated diet for 12 weeks, selenium-deficient rats or selenium-normal rats were then treated with tempol (1 mM) for 4 weeks. (A, B) Systolic- (SBP, A) and diastolic blood pressures (DBP, B) in selenium-deficient rats treated with tempol (*P < 0.05 vs Se-normal; #P < 0.05 vs Se-deficiency, n=5/group). (C, D) 24-hours urine volume (C) and urine sodium excretion (UNa, D) in selenium-deficient rats treated with tempol (*P < 0.05 vs Se-normal; #P < 0.05 vs Se-deficiency, n=5/group). (E, F) The mRNA (E) and protein expression (F) of AT1R in selenium-deficient rats treated with tempol (*P < 0.05 vs Se-normal; #P < 0.05 vs Se-deficiency, n=5/group). (G) Effect of tempol in the serum MDA levels in selenium-deficient rats (*P < 0.05 vs Se-normal; #P < 0.05 vs Se-deficiency, n=5/group).