Table 3.
Comparison of Patients who were on TPN/EN (at baseline or 48 weeks) to Patients Never on TPN
| On TPN/EN | Never on TPN/EN | P† | |
|---|---|---|---|
| N | 47 (4.8%) | 924 (95.2%) | |
| Characteristics at Visit | |||
| Etiology | 35 IGp, 12 DGp | 544 IGp, 324 DGp, 51 PFGp | 0.12 |
| Age | 38.4 (19, 63) | 45 (18, 84) | 0.002 |
| Female Sex | 43 (92%) | 774 (84%) | 0.22 |
| BMI | 21.0 (18.6, 24.2) | 27.1 (22.1, 32.6) | <0.001 |
| Waist Circumference (cm) – mean (SD) | 80.0 (15.7) | 92.4 (19.1) | <0.001 |
| Waist-To-Hip Ratio – mean (SD) | 0.87 (0.11) | 0.89 (0.09) | 0.18 |
| Waist-To-Hip Ratio Health Risk – no. (%) | |||
| Low | 14 (29.8%) | 216 (23.4%) | 0.02 |
| Moderate | 15 (31.9%) | 177 (19.2%) | |
| High | 18 (38.3%) | 530 (57.4%) | |
| Nausea subscore | 3.3 (2.2, 4.2) | 2.0 (1.0, 3.3) | <0.001 |
| Early satiety subscore | 4.0 (3.3, 4.5) | 3.3 (2.5, 4.0) | <0.001 |
| Bloating subscore | 3.0 (2.0, 4.5) | 3.0 (2.0, 4.0) | 0.77 |
| GCSI Score | 3.2 (2.8, 4.0) | 2.9 (2.0, 3.5) | 0.001 |
| Upper abdominal pain | 4.0 (3.0, 4.6) | 3.0 (1.5, 4.0) | <0.001 |
| GERD Score | 2.6 (1.6, 3.2) | 1.7 (0.8, 2.9) | 0.002 |
| SF-36 PCS | 26.6 (19.3, 31.2) | 33.4 (26.1, 41.9) | <0.001 |
| SF-36 MCS | 37.0 (26.8, 48.4) | 40.5 (29.9, 51.8) | 0.34 |
| PAGI-QOL overall score | 1.9 (1.0, 2.8) | 2.8 (1.9, 3.6) | <0.001 |
| Gastric retention 4 hrs (%) | 36 (20, 51) | 26 (17, 45) | 0.06 |
| Severe Retention (4 hr R > 35%) | 23/45 (51.1%) | 332/916 (36.2%) | 0.06 |
| Volume Water WLST (ml) | 180 (100, 330) | 355 (237, 500) | <0.001 |
| Hospitalized in past year (%) | 31/47 (66.0%) | 229/923 (24.8%) | <0.001 |
| Prokinetic Use | 21/47 (44.7%) | 318/924 (34.4%) | 0.16 |
| Domperidone Use | 10/47 (21.3%) | 109/924 (11.8%) | 0.07 |
| Gastric stimulator | 13/47 (27.7%) | 89/924 (9.6%) | <0.001 |
| Narcotic Use | 25/47 (53.2%) | 321/924 (34.7%) | 0.01 |
NOTE: Values reported are median (Q1, Q3) or N (%) unless otherwise noted. Values shown correspond to the patient’s most recent visit, except for patients on TPN/EN at baseline and not 48 weeks, where values shown are from the baseline visit.
Waist to hip ratio health risk is reported as low (waist circumference ≤0.80 for women and ≤0.95 for men), medium (0.81 - 0.85 for women and 0.96-1.0 for men), and high (≥0.86 for women and >1.0 for men).
†
P values for Fisher’s exact test for differences in categorical measures or Wilcoxon rank sum tests or t tests for differences in continuous measures