Table 4.
Multivariable model for association between patient characteristics and use of TPN/EN at either baseline and/or 48 weeks.
Odds Ratio† [95% CI] | P | |
---|---|---|
BMI (per 1 kg/m2 unit) | 0.87 [0.81, 0.93] | < 0.001 |
Early Satiety Score (per 1 point) | 1.79 [1.16, 2.75] | 0.008 |
Nausea (per 1 point) | 1.58 [1.20, 2.08] | 0.001 |
Bloating (per 1 point) | 0.76 [0.59, 0.98] | 0.03 |
Narcotic use (yes v no) | 2.33 [1.15, 4.69] | 0.02 |
A total of 837 patients were included in the model, with 38 (4.5%) having ever been on TPN/EN and 799 (95.5%) not. The final model shown was selected using a forward and backward stepwise selection approach with a minimum AIC for selection criteria.
Candidate factors analyzed included acute vs. insidious symptom onset, BMI, number of hospitalizations in prior year, PAGI-QOL overall score, narcotic use, gastric retention at 4 hours, nausea/vomiting subscore, bloating subscore, early satiety/postprandial distension subscore, and upper abdominal scores.
NOTE: CI = Confidence Interval
Odds ratios from a multivariable logistic regression model with use of TPN/EN as the dependent variable and all characteristics shown in the table as independent variables.