Table 4.

Validation of EoE GWAS signals. Table shows the strongest p-value in the EoE GWAS of African American of SNPs in high LD (r² ≥ 0.6) with the 14 EoE variants from GWAS Catalog. Out of the 26 loci in the GWAS Catalog, only 14 were found in the GWAS data.

RSID	REGION	Pos37	MAF	OR	P	Catalog SNP	Catalog MAF	R2	GENE	Catalog_P
rs2279293	15q22.2	61057357	0.496	1.58	0.000673	rs2279293	0.145	1	RORA	5.00E-11
rs4593605	9p24.1	5107278	0.155	1.57	0.006845	rs62541556	0.251	0.8189	JAK2	4.00E-08
rs17228227	15q13.3	31537646	0.044	0.392	0.032718	rs8041227	0.28	0.968	LINC02352 - KLF13	6.00E-10
rs61894547	11q13.5	76248630	0.0129	0.191	0.10543	rs61894547	0.043	1	EMSY	5.00E-15
rs11124247	2p23.1	31411155	0.0234	0.423	0.150938	rs143457388	0.047	0.8676	CAPN14	3.00E-16
rs2307472	2p22.2	37376247	0.0125	0.262	0.189446	rs143457389	0.046	0.6662	PRKD3	3.00E-16
rs3806932	5q22.1	110405675	0.363	1.183	0.201364	rs3806932	0.46	1	TSLP	3.00E-09
rs371915	16q24.1	84578241	0.174	1.24	0.204934	rs371915	0.13	1	MEAK7	2.00E-08
rs887992	2q12.1	103524931	0.324	0.862	0.276979	rs887992	0.362	1	TMEM182	4.00E-10
rs2545357	19q13.11	33104610	0.448	0.891	0.384192	rs3815700	0.14	0.7399	ANKRD27	2.00E-09
rs2753961	6p21.33	31754830	0.0535	1.23	0.421398	rs599707	0.114	0.9838	SNHG32 - NEU1	3.00E-09
rs56062135	15q22.33	67455630	0.0947	1.114	0.597795	rs56062135	0.228	1	SMAD3	4.00E-10
rs2706349	5q31.1	131906760	0.376	1.067	0.628782	rs2106984	0.212	0.8568	RAD50	4.00E-08
rs34443974	16p13.13	11179305	0.0695	1.065	0.790302	rs35099084	0.222	0.8598	CLEC16A	2.00E-12