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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: J Allergy Clin Immunol Pract. 2023 Mar 21;11(5):1361–1373. doi: 10.1016/j.jaip.2023.03.011

Figure 1.

Figure 1.

A. JAK-STAT pathway, ultimately leading to regulation of gene transcription in the nucleus. B. Cytokine binding and activation of a variety of receptors leads to signaling through the JAK-STAT pathway to cause inflammation. Modified figure reprinted with permission from Chovatiya and Paller. J Allergy Clin Immunol 2021;148:927–940.