Table 2.
CRC incidences after H. pylori eradication compared with the expected incidences in the matched general population.
| CRC | Colon cancer | Rectal cancer | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Observation period | Person-years | Observed/expected number of cases | SIR (95% CI) | Person-years | Observed/expected number of cases | SIR (95% CI) | Person-years | Observed/expected number of cases | SIR (95% CI) |
| Overall | 937738.5 | 1417/1377.5 | 1.03 (0.97–1.09) | 939113.2 | 1026/854.6 | 1.20 (1.12–1.29) | 940742.9 | 476/528.0 | 0.90 (0.81–0.999) |
| Years after eradication | |||||||||
| 1–5 years | 461084.4 | 691/608.7 | 1.14 (1.04–1.24) | 461410.3 | 503/374.4 | 1.34 (1.22–1.48) | 461883.5 | 219/235.5 | 0.93 (0.80–1.08) |
| 6–10 years | 320616.2 | 492/494.0 | 1.00 (0.90–1.10) | 321182.3 | 345/307.4 | 1.12 (0.99–1.27) | 321898.6 | 179/188.7 | 0.95 (0.80–1.12) |
| ⩾11 years | 156037.9 | 234/274.8 | 0.85 (0.74–0.99) | 156520.6 | 178/172.7 | 1.03 (0.87–1.22) | 156960.8 | 78/103.8 | 0.75 (0.58–0.97) |
CI, confidence interval; CRC, colorectal cancer; SIR, standardized incidence ratio.