TABLE 2.
Univariate analyses of the factors associated with irAEs.
| irAE (n = 44) | Non-irAE (n = 62) | p-value | |
|---|---|---|---|
| Sex | NS | ||
| Male, n (%) | 33 (75%) | 52 (84%) | |
| Female, n (%) | 11 (25%) | 10 (16%) | NS |
| Age | 58 ± 11 | 60 ± 11 | NS |
| Cirrhosis, n (%) | 29 (66%) | 40 (65%) | NS |
| Basal metabolic disease, n (%) | 33 (75%) | 45 (73%) | NS |
| Extrahepatic metastasis, n (%) | 23 (52%) | 25 (40%) | NS |
| Hypertension, n (%) | 17 (39%) | 22 (35%) | NS |
| Hyperlipidemia, n (%) | 4 (9%) | 3 (5%) | NS |
| Diabetes, n (%) | 10 (23%) | 16 (26%) | NS |
| BMI (kg/m2) | 23.7 ± 3.7 | 22.6 ± 3.0 | 0.037 |
| Glucose (mmol/L) | 5.5 ± 1.7 | 6.1 ± 2.4 | NS |
| Triglyceride (mmol/L) | 1.1 ± 0.3 | 1.0 ± 0.3 | NS |
| Total cholesterol (mmol/L) | 4.1 ± 1.0 | 4.2 ± 1.0 | NS |
| Free fatty acid (mmol/L) | 0.6 ± 0.3 | 0.6 ± 0.3 | NS |
| PLT (109/L) | 139.2 ± 79.8 | 151.2 ± 88.7 | NS |
| ALT (IU/L) | 40.4 ± 30.q | 38.0 ± 25.5 | NS |
| AST (IU/L) | 55.6 ± 44.3 | 57.3 ± 40.4 | NS |
| AKP (IU/L) | 171.4 ± 117.4 | 170.6 ± 90.2 | NS |
| GGT (IU/L) | 140.9 ± 111.4 | 163.4 ± 119.5 | NS |
| TBIL (μmol/L) | 20.6 ± 10.5 | 29.3 ± 35.6 | NS |
| ALB (g/L) | 35.3 ± 5.2 | 35.1 ± 5.3 | NS |
| TBA (μmol/L) | 16.6 ± 17.8 | 20.1 ± 28.1 | NS |
| Na (mmol/L) | 139.1 ± 3.9 | 138.6 ± 3.8 | NS |
| K (mmol/L) | 4.0 ± 0.5 | 4.0 ± 0.5 | NS |
| Cl (mmol/L) | 103.0 ± 4.5 | 101.5 ± 4.3 | NS |
| CO2 (mmol/L) | 25.8 ± 2.8 | 25.9 ± 2.6 | NS |
| Ca (mmol/L) | 2.2 ± 0.2 | 2.2 ± 0 | NS |
| P (mmol/L) | 1.1 ± 0.2 | 1.1 ± 0.12 | NS |