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. 2023 May 7;13(5):e1260. doi: 10.1002/ctm2.1260

FIGURE 1.

FIGURE 1

Cytoplasmic BATF2 expression negatively correlates with the prognosis of colorectal cancer (CRC) patients. (A–C) Representative immunohistochemistry (IHC) staining of BATF2 expression in CRC and pericarcinoma tissues from 184 CRC patients (A and B), and quantification of IHC images by using ImageJ software (C). Scale bar: 100 µm. (D and E) Western blot analysis of nuclear and cytoplasmic BATF2 expression in fresh frozen CRC and pericarcinoma tissues from three CRC patients (D) and CCD 841 CoN and HCT116 cells (E). C: carcinoma; P: pericarcinoma. (F and G) Immunofluorescence analysis of BATF2 in CCD 841 CoN and HCT116 cells (F) and quantification of BATF2 expression by using ImageJ software (G). Scale bar: 10 µm. (H–J) Kaplan–Meier estimates of overall survival time based on cytoplasmic BATF2 expression levels from 184 CRC patients, both at stage I/II (n = 115) and stage III/IV (n = 69). Data are expressed as mean ± SD. * p < .05, ** p < .01, *** p < .001.