Table 1.

Comparison of presentation and diagnosis of intraplacental choriocarcinoma and gestational choriocarcinoma.

	Intraplacental choriocarcinoma	Gestational choriocarcinoma
Presentation	Routine evaluation of placenta after delivery Evaluation of placenta after non-reassuring fetal status or stillbirth Evaluation of products of conception after pregnancy termination or early pregnancy loss Gross placental lesion noted after delivery Vaginal bleeding during pregnancy Symptoms of metastases (respiratory, neurologic)	Evaluation of pregnancy tissue, including molar gestation and early pregnancy loss Vaginal bleeding or bleeding from metastases Other symptoms of metastases (respiratory, neurologic) Persistently elevated hCG
Diagnosis	Histopathologic diagnosis	Clinical diagnosis, including - Histopathology - Rise or plateau of hCG - Symptoms or radiologic evidence of metastases