Table 1.
Characteristics of the 25 case-control studies from the Ovarian Cancer Association Consortium, conducted in Asia, Australia, Europe, and North America from 1989 to present and included in the lifetime ovulatory years (LOY) analyses
| Study | Region | Study name | Study period | Case type | Method of data collection | Age, mean (SD), y | Control participants, No. (%) | Case patients, No. (%) |
|---|---|---|---|---|---|---|---|---|
| AUS (16) | Australia | Australian Ovarian Cancer Study/Australian Cancer Study | 2002-2006 | Population-based | Self-completed questionnaire | 56.88 (12.28) | 1506 (43.2) | 1984 (56.8) |
| BAV (17) | Germany | Bavarian Ovarian Cancer Cases and Controls | 2002-2006 | Hospital or Clinic-based | Interview | 57.31 (13.77) | 629 (47.9) | 684 (52.1) |
| CON (18) | USA | Connecticut Ovarian Cancer Study | 1998-2003 | Population-based | Interview | 55.27 (11.04) | 551 (52.6) | 497 (47.4) |
| DOV (19) | USA | Diseases of the Ovary and their Evaluation | 2002-2009 | Population-based | Interview | 55.78 (9.26) | 1849 (54.2) | 1562 (45.8) |
| GER (20) | Germany | German Ovarian Cancer Study | 1993-1996 | Population-based | Self-completed questionnaire | 55.07 (12.24) | 533 (67.4) | 258 (32.6) |
| HAW (21) | USA | Hawaii Ovarian Cancer Case-Control Study | 1993-2008 | Population-based | Interview | 54.98 (14.28) | 1103 (55.2) | 895 (44.8) |
| HOP (22) | USA | Hormones and Ovarian cancer PrEdiction | 2003-2009 | Population-based | Interview | 58.66 (12.52) | 1802 (68.3) | 836 (31.7) |
| JPN (23) | Japan | Hospital-based Research Program at Aichi Cancer Center | 2001-2005 | Hospital or Clinic-based | Interview | 52.36 (11.17) | 233 (60.5) | 152 (39.5) |
| MAY (24) | USA | Mayo Clinic Ovarian Cancer Case-Control Study | 1999-2018 | Hospital or Clinic-based | Interview | 60.51 (13.58) | 2299 (55.5) | 1846 (44.5) |
| MCC (25)a | Australia | Melbourne Collaborative Cohort Study | 1990-2008 | Defined cohort | Self-completed questionnaire | 64.07 (9.62) | 471 (73.1) | 173 (26.9) |
| NCO (26) | USA | North Carolina Ovarian Cancer Study | 1999-2008 | Population-based | Interview | 55.28 (11.53) | 1085 (47.6) | 1195 (42.4) |
| NEC (27) | USA | New England Case Control Study | 1992-2003 | Population-based | Interview | 53.54 (12.35) | 2100 (50.0) | 2075 (49.7) |
| NJO (28) | USA | New Jersey Ovarian Cancer Study | 2002-2008 | Population-based | Interview | 61.48 (11.60) | 458 (65.9) | 237 (34.1) |
| NTH (29,30) | Netherlands | Nijmegen Ovarian Cancer Study | 1997-2008 | Population-based | Self-completed questionnaire | 55.90 (10.79) | 600 (69.4) | 265 (30.6) |
| OVA | Canada | Ovarian Cancer in Alberta and British Columbia | 2002-2012 | Population-based | Self-completed questionnaire 2002-2004; interview 2004-2012 | 56.81 (10.62) | 2698 (62.2) | 1637 (37.8) |
| POL (31) | Poland | Polish Ovarian Cancer Case Control Study | 2000-2003 | Population-based | Interview | 55.70 (10.62) | 1128 (79.3) | 294 (20.7) |
| SON (32) | Canada | Southern Ontario Ovarian Cancer Study | 1989-1993 | Population-based | Interview | 56.86 (11.97) | 564 (55.6) | 450 (44.4) |
| STA (33) | USA | Family Registry for Ovarian Cancer AND Genetic Epidemiology of Ovarian Cancer | 1997-2001 | Population-based | Interview | 47.77 (10.07) | 567 (46.0) | 665 (54.0) |
| SWH (34) | China | Shanghai Women’s Health Study | 1996-present | Defined cohort | Interview | 53.36 (9.70) | 986 (86.6) | 152 (13.4) |
| TBO (35) | USA | Tampa Bay Ovarian Cancer Study | 2000-present | Population-based | Interview | 60.53 (10.85) | 205 (41.8) | 285 (58.2) |
| TOR (36) | Canada | Familial Ovarian Tumour Study (FOTS) AND Health Watch (HW) | 1995-1999 and 2000-2003 | Population-based | Interview | 56.62 (12.77) | 322 (21.6) | 1167 (78.4) |
| UCI (37) | USA | University California Irvine Ovarian Study | 1993-2005 | Population-based | Interview | 54.29 (13.17) | 614 (49.1) | 636 (50.9) |
| UKO (38) | UK | United Kingdom Ovarian cancer Population Study | 2006-2010 | Hospital or Clinic-based | Interview | 63.06 (8.93) | 1182 (58.5) | 839 (41.5) |
| USC (39-41) | USA | Los Angeles County Case-Control Studies of Ovarian Cancer | 1992-2009 | Population-based | Interview | 55.07 (12.41) | 2595 (52.2) | 2380 (47.8) |
| VTL (42)a | USA | VITamins And Lifestyle Cohort Study | 2000-2010 | Defined cohort | Self-completed questionnaire | 68.19 (7.62) | 124 (54.6) | 103 (45.4) |
| Total | 56.55 (12.20) | 26204 (55.2) | 21267 (44.8) |
a
Employed a nested-case control study design within a cohort study.