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. 2023 Apr 24;11:1091666. doi: 10.3389/fcell.2023.1091666

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Copyright © 2023 Siewert, Reiz, Krug, Heggemann, Mangold, Dickten and Ludwig.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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AD syCL/P genes are expressed in more cell types and have higher average expression levels compared with nsCL/P genes. (A) Boxplot of the percentages of cell types expressing the gene groups of syCL/P, nsCL/P, and overlapping genes at E11.5 (B) Boxplot of average log2 expression levels of the gene groups of syCL/P, nsCL/P, and overlapping genes at E11.5. (C) Venn diagram of non-syndromic, AR syndromic, and AD syndromic CL/P gene lists. (*p < 0.05). Data on the remaining time points are provided in Supplementary Figure S2.