Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 May 5;220(8):e20221166. doi: 10.1084/jem.20221166

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 Yang et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 7. — IFNAR1 on Tregs are important for rMVA-induced antitumor effects in two murine tumor models. (A) Kaplan–Meier survival curve of MC38-bearing Ifnar1^fl/fl and Foxp3^CreIfnar1^fl/fl mice treated with IT rMVA or PBS (n = 5 or 10; *P < 0.05, **P < 0.01, ***P < 0.001, Mantel-Cox test). (B) MC38 tumor volumes over days in Ifnar1^fl/fl and Foxp3^CreIfnar1^fl/fl mice treated with IT rMVA or PBS control. (C) Kaplan–Meier survival curve of B16-F10-bearing Ifnar1^fl/fl and Foxp3^CreIfnar1^fl/fl mice treated with IT rMVA (n = 9; *P < 0.05, Mantel-Cox test). (D) B16-F10 tumor volumes over days in Ifnar1^fl/fl and Foxp3^CreIfnar1^fl/fl mice treated with IT rMVA.