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. 2023 May 7;18:107. doi: 10.1186/s13023-023-02705-6

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — The expression and splicing of SETBP1 in vivo. A The mRNA expression level of SETBP1 in D1, M1 and X1. B The results of agarose gel electrophoresis of RT-PCR. C The schematic diagram of the splicing of SETBP1 in vivo in D1, M1 and X1. D The cloning and sequencing results of X1 and the sequencing results of D1 and M1. Except for the mutation (SETBP1 c.1724_1727del), a 40 bp deletion in D1 (band c) was found (c.1795_1834del). A 49 bp deletion (c.1472_1520del) was found in X1 (band b)