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. 2023 Apr 13;2(5):pgad134. doi: 10.1093/pnasnexus/pgad134

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© The Author(s) 2023. Published by Oxford University Press on behalf of National Academy of Sciences.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1. — Experimental design of DG hilus Sst⁺ cell manipulation. A) Immunofluorescence staining of coronal sections from an AAV-hSyn-DIO-mCherry mouse showing DAPI counterstain (left: DAPI; middle: mCherry expression; right: merged image). B) Immunofluorescence colabeling of coronal sections from an AAV-hSyn-DIO-mCherry mouse (left: Sst labeling with Alexa Fluor 488; middle: mCherry; right: merged image, with DAPI). C) Top: chronic chemogenetic inhibition of DG hilus Sst⁺ cells. Bottom: subchronic chemogenetic inhibition of DG hilus Sst⁺ cells.