. 2023 Apr 13;2(5):pgad134. doi: 10.1093/pnasnexus/pgad134

Table 1.

Expression of molecular markers, behavioral and morphological effects of CCI and SCI of DG hilus Sst⁺ interneurons.

	c-Fos	Sst	GAD67	Iba1	MWM	NOR	YM	DG spine density	DG dendritic length	CA1 spine density	CA1 dendritic length
CCI	↑	↓	↓	↑	↓	↓	↓	↓	↓	↓	↓
SCI	↑	−	−	−	−	−	↓	↓	↓	−	↓

The displayed results are comparing outcomes in AAV-hSyn-DIO-hM4D(Gi)-mCherry mice compared with AAV-hSyn-DIO-mCherry mice. Most molecular and behavioral changes require CCI.

	c-Fos	Sst	GAD67	Iba1	MWM	NOR	YM	DG spine density	DG dendritic length	CA1 spine density	CA1 dendritic length
CCI	↑	↓	↓	↑	↓	↓	↓	↓	↓	↓	↓
SCI	↑	−	−	−	−	−	↓	↓	↓	−	↓

	c-Fos	Sst	GAD67	Iba1	MWM	NOR	YM	DG spine density	DG dendritic length	CA1 spine density	CA1 dendritic length
CCI	↑	↓	↓	↑	↓	↓	↓	↓	↓	↓	↓
SCI	↑	−	−	−	−	−	↓	↓	↓	−	↓

	c-Fos	Sst	GAD67	Iba1	MWM	NOR	YM	DG spine density	DG dendritic length	CA1 spine density	CA1 dendritic length
CCI	↑	↓	↓	↑	↓	↓	↓	↓	↓	↓	↓
SCI	↑	−	−	−	−	−	↓	↓	↓	−	↓