Table 3.

OxS markers and antioxidant capacity by study group.

Parameter	Placebo Group n = 23	Experimental Group n = 25	p-value
Lipoperoxides [µmol/L]
Baseline	0.23 ± 0.05	0.29 ± 0.11
6 months	0.21 ± 0.02	0.19 ± 0.03*	0.01
Protein carbonylation [nmol/mg]
Baseline	30.3 ± 5.3	31.6 ± 5.3
6 months	34.6 ± 6.9	28.7 ± 4.6*	0.05
8-OHdG [ng/mL]
Baseline	30.3 ± 8.0	32.0 ± 9.3
6 months	31.1 ± 8.5	21.5 ± 7.4*	0.01
SOD [U/mL]
Baseline	177 ± 13	181 ± 7
6 months	163 ± 14	185 ± 6*	0.05
GPx [U/L]
Baseline	5007 ± 2091	6611 ± 1792
6 months	4315 ± 1362	6726 ± 2864	0.08
H2O2 Inhibition [µmol/min]
Baseline	3.26 ± 1.1	3.14 ± 1.19
6 months	2.42 ± 0.5	3.77 ± 1.03*	0.01
TAS [mmol/L]
Baseline	1.33 ± 0.19	1.06 ± 0.19
6 months	1.05 ± 0.25	1.26 ± 0.25*	0.001
TOS [µmol H2O2 Equiv./L]
Baseline	24.9 ± 2.2	29.1 ± 4.3
6 months	28.5 ± 4.2	24.7 ± 4.9*	0.05

The data are expressed as the mean ± standard deviation. ANOVA of repeated measures, significance level 95%, p < 0.05. 8-OHdG: 8-hydroxydeoxyguanosine; SOD, superoxide dismutase; GPx, glutathione peroxidase; TAS: total antioxidant status. TOS: total oxidizing state. *Baseline statistical significance vs 6 months inter-group.