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. 2023 Apr 28;13(1):50–53. doi: 10.5415/apallergy.0000000000000022

Table 2.

Clinical manifestations of mast cell activation syndrome [17, 18]

Organ system Clinical symptoms
Systemic Anaphylaxis, syncope, fatigue
Dermatologic Flushing, skin rash, pruritus, urticaria
Cardiovascular Hypotension, shock, chest pain, tachycardia
Respiratory Wheezing
Musculoskeletal Arthralgia, myalgia, degenerative disc disease, osteoporosis/osteopenia
Gastrointestinal Nausea, vomitus, abdominal pain, gastroesophageal reflux, diarrhea, esophagitis, abdominal cramp, bloating, malabsorption
Neurological Cognitive impairment, brain fog, dizziness, vertigo, migraine, paresthesia, peripheral neuropathy