| Study | Reason for exclusion |
|---|---|
| Al Haddad 1996 | Allocation: randomised. Participants: 49 people with mania, acute psychoses or exacerbation of a chronic psychosis ‐ no diagnostic information on whether anyone had delusional disorder. |
| Davies 2007 | Allocation: randomised. Participants: 275 people with a DSM‐IV diagnosis of schizophrenia, schizoaffective disorder or delusional disorder (10). Intervention: one of a range of first‐generation antipsychotic medications versus one of a range of second‐generation antipsychotic medications. Outcome: no usable outcomes as no separate reporting of results relevant to delusional disorder presented. |
| Farhall 2009 | Allocation: randomised. Participants: 94 people with a diagnosis of either schizophrenia, schizoaffective disorder, delusional disorder (6) or mood disorder with psychotic features. Intervention: CBT for psychosis + TAU (treatment as usual including, for most, antipsychotic medication) versus TAU (treatment as usual including, for most, antipsychotic medication). Outcome: no usable outcomes as no separate reporting of results relevant to delusional disorder presented. |
| Fear 2002 | Allocation: randomised, cross‐over. Diagnosis: DSM‐IV delusional disorder. Interventions: risperidone versus placebo, N = 4. Outcomes: mental state (BPRS, MADS, PANSS), leaving the study early ‐ no usable data, reported as case report of 1 person ‐ study closed because of poor recruitment. Dr Fear contacted and kindly attempted to obtain original data, but this was not possible. |
| Foster 2010 | Allocation: randomised. Participants: 21 people with schizophrenia and 3 with a diagnosis of either schizoaffective disorder or delusional disorder. Intervention: W‐CBT (cognitive behavioural worry intervention) + standard medical care* versus TAU. Outcome: no usable outcomes as no separate reporting of results relevant to delusional disorder presented. *Inferred that W‐CBT was in addition to standard medical care including medication as no description of medication regimes being stopped etc. |
| Gafoor 2010 | Allocation: randomised. Participants: 144 people with a first or second episode of non‐affective psychosis (schizophrenia, schizotypal and delusional disorders). No separate identification of people with delusional disorder. Intervention: "Specialist services*" versus "care as usual by community mental health teams (CMHTs)". Outcome: no usable outcomes as no separate reporting of results relevant to delusional disorder presented. Specialist services*: "including low dose atypical antipsychotic regimens, cognitive–behavioural therapy based on manualised protocols, family counselling and vocational strategies based on established protocols." |
| Nordentoft 2009 | Allocation: randomised. Participants: people with schizophrenia or schizophrenia‐like psychosis (schizotypal disorder, persistent delusional disorder, acute and transient psychotic disorder, induced delusional disorder, schizoaffective disorder, other non‐organic psychotic disorder). Intervention: modified assertive community treatment versus treatment in a community mental health centre. Outcome: no usable outcomes as no separate reporting of results relevant to delusional disorder presented. |
| Çetin 2000 | Allocation: randomised. Participants: 30 people with "monosymptomatic hypochondriacal psychosis". Intervention: 6 mg risperidone daily versus 4 mg pimozide daily. Outcome: PANSS, CGI, UKU, Extrapyramidal Symptom Rating Scale; only inexact P values reported ‐ no usable outcomes (authors unresponsive). |
CGI: Clinical Global Impression Scale BPRS: Brief Psychiatric Rating Scale CBT: cognitive behavioural therapy MADS: Maudsley Assessment of Delusions Schedule PANSS: Positive and Negative Symptoms Scale TAU: treatment as usual