Table 1.
Baseline characteristics of neonates screened for retinopathy of prematurity in the neonatal intensive care unit across all time periodsa
| Study parameter | All time periods N = 1633 |
Time period 1b n = 198 | Time period 2 n = 533 | Time period 3 n = 491 | Time period 4 n = 411 | P valuec |
|---|---|---|---|---|---|---|
| Sex, no. (%) | ||||||
| Female | 761 (47.0) | 87 (44.2) | 245 (46.9) | 218 (44.6) | 211 (51.5) | 0.17d |
| Male | 858 (53.0) | 110 (55.8) | 278 (53.2) | 271 (55.4) | 199 (48.4) | |
| GA, weeks, mean ± SD | 28.3 ± 2.87 | 28.2 ± 3.00 | 28.4 ± 2.94 | 28.0 ± 2.75 | 28.3 ± 2.86 | 0.16 |
| <28 weeks, no. (%) | 701 (42.9) | 85 (42.9) | 230 (43.2) | 221 (45.0) | 165 (40.2) | 0.54 |
| ≥28 weeks, no. (%) | 932 (57.1) | 113 (57.1) | 303 (56.9) | 270 (55.0) | 246 (59.9) | |
| <32 weeks, no. (%) | 1463 (89.6) | 170 (85.9) | 470 (88.2) | 453 (92.3) | 370 (90.0) | 0.05 |
| ≥32 weeks, no. (%) | 170 (10.4) | 28 (14.1) | 63 (11.8) | 38 (7.7) | 41 (10.0) | |
| BW, g, mean ± SD | 1079.1 ± 378.60 | 1086.5 ± 391.56 | 1108.0 ± 402.87 | 1046.4 ± 363.54 | 1075.9 ± 354.68 | 0.08 |
| <1250 g, no. (%) | 1064 (65.2) | 130 (65.7) | 337 (63.2) | 326 (66.4) | 271 (65.9) | 0.72 |
| ≥1250 g, no. (%) | 569 (34.8) | 68 (34.3) | 196 (36.8) | 165 (33.6) | 140 (34.1) | |
| <1500 g, no. (%) | 1435 (87.9) | 175 (88.4) | 453 (85.0) | 445 (90.6) | 362 (88.1) | 0.05e |
| ≥1500 g, no. (%) | 198 (12.1) | 23 (11.6) | 80 (15.0) | 46 (9.4) | 49 (11.9) | |
BW, birth weight; GA, gestational age; SD, standard deviation.
a
Time periods: (1) November 1, 2018, to March 15, 2019; (2) March 16, 2019, to August 2, 2019; (3) November 1, 2019, to March 15, 2020; (4) March 16, 2020, to August 2, 2020 (lockdown period).
b
Data available for 4/7 institutions.
c
A P value of ≤0.05 was considered significant.
d
Significant difference between time periods 3 and 4 (P = 0.04).
e
Significant difference between time periods 2 and 3 (P < 0.01).