TABLE 2.
Clinical scores
| Group | Strain | Inoculum (CFU/lung) | No. of survivors | Clinical scorea (mean ± SD)
|
|
|---|---|---|---|---|---|
| All calves | Surviving calves | ||||
| 1 | SH2099 | 3 × 108 | 7b | 3.4 ± 4.5 | 1.9 ± 1.6 |
| 2 | SH2099 | 3 × 109 | 4c | 9.0 ± 5.2 | 5.8 ± 5.4 |
| 3 | SH789 | 3 × 108 | 5 | 3.4 ± 4.6 | 0.8 ± 1.1 |
| 4 | SH789 | 3 × 109 | 1 | 12 ± 2.0 | 13 |
a
Assigned as follows: Depressed and/or off feed, 1; sneezing and/or coughing, 2; purulent nasal discharge, 1; purulent ocular discharge, 1; respiratory distress, 3; oral and/or nasal mucosal lesions, 4; diarrhea (loose, watery, or bloody stools), 3; moderate rectal temperature elevation (103.5 to 105°C), 3; severe rectal temperature elevation (>105°C), 4 (maximum score, 22).
b
P = 0.03, group 1 versus group 3.
c
P = 0.005, group 2 versus group 4.