TABLE 3.
Response rates by number of previous cytotoxic chemotherapies.
| Response rate a | Group A | Group B | ||||
|---|---|---|---|---|---|---|
| No. | % | 95% CI | No. | % | 95% CI | |
| One regimen | 19 | 18 | ||||
| Overall response | 5 | 26.3 | 9.1 to 51.2 | 4 | 22.2 | 6.4 to 47.6 |
| Complete response | 0 | 0 | 0 | 0 | ||
| Partial response | 5 | 26.3 | 4 | 22.2 | ||
| Stable disease | 6 | 31.6 | 8 | 44.4 | ||
| Progressive disease | 6 | 31.6 | 5 | 27.8 | ||
| Not evaluable | 2 | 10.5 | 1 | 5.6 | ||
| Two regimens or more | 20 | 21 | ||||
| Overall response | 3 | 15.0 | 3.2 to 37.9 | 5 | 23.8 | 8.2 to 47.2 |
| Complete response | 0 | 0 | 0 | 0 | ||
| Partial response | 3 | 15.0 | 5 | 23.8 | ||
| Stable disease | 8 | 40.0 | 7 | 33.3 | ||
| Progressive disease | 9 | 45.0 | 8 | 38.1 | ||
| Not evaluable | 0 | 0 | 1 | 4.8 | ||
a
Objective response by investigator review per Response Evaluation Criteria in solid tumors, version 1.1.