TABLE 4.

Proliferation of T-cell lines in response to Ag85B and its peptides in the presence of HLA-DR-typed APC^a

APC HLA-DR	Proliferation (SI) of T-cell line S-45 (HLA-DR2,7,51,53)					Proliferation (SI) of T-cell line S-47 (HLA-DR2,51)		Proliferation (SI) of T-cell line S-39 (HLA-DR1,4,53), Ag85B
	Ag85B	Peptide p13	Peptide p16	Peptide p17	Peptide p26	Ag85B	Peptide p6
2,7,51,53	171	41	41	97	12	3.5	3.4	NDb
7,53	142	60	76	62	17	1.2	2.0	ND
5,7,52	78	3.8	13	7.7	7.0	ND	ND	ND
4,7,53	44	2.2	14	6.1	1.7	ND	ND	ND
4,5,52,53	1.4	2.1	2.7	1.3	1.4	4.2	1.9	ND
2,51	2.2	1.7	1.4	1.0	0.9	7.2	7.2	0.8
2,6,51,52	1.3	1.1	0.8	1.1	1.0	13	7.6	ND
2,4,51,53	1.7	1.1	1.0	1.0	1.1	ND	ND	ND
1,6,52	ND	ND	ND	ND	ND	1.1	1.1	1.1
1,4,53	ND	ND	ND	ND	ND	ND	ND	65
3,10,52	ND	ND	ND	ND	ND	ND	ND	1.2
1,7,53	ND	ND	ND	ND	ND	ND	ND	83
5,6,52	ND	ND	ND	ND	ND	ND	ND	0.8
3,5,52	ND	ND	ND	ND	ND	ND	ND	0.4
HLA-DR restriction	DR7	DR7	DR7	DR7	DR7	DR2	DR2	DR53

^aPositive responses (SI ≥ 5) are given in bold. 

^bND, not determined.