Table 2.
Outcomes at 2 years follow-up
| Pre-AOC | Post-AOC | P valuea | |
|---|---|---|---|
| Adverse outcome (severe NDI or death) | 41 (17.9) | 47 (24.0) | 0.12 |
| Severe NDI, n (%) | 10 (5.1) | 13 (8.0) | 0.25 |
| Early death, n (%) | 30 (10.2) | 32 (10.8) | 0.82 |
| Late death, n (%) | 1 (0.4) | 2 (0.8) | 1.00 |
| Mild-moderate NDI, n (%) | 82 (38.5) | 78 (43.8) | 0.29 |
| BSID III composite motor score, median [IQR] | 97 [89 – 107] | 98 [89–109] | 0.18 |
| Score 70–85, n (%) | 25 (12.6) | 25 (12.8) | 0.94 |
| Score < 70, n (%) | 5 (2.5) | 11 (5.6) | 0.12 |
| BSID III composite cognitive score, median [IQR] | 96 [87–101] | 96 [91–105] | 0.23 |
| Score 70–85, n (%) | 31 (13.4) | 26 (12.7) | 0.85 |
| Score < 70, n (%) | 7 (3.0) | 7 (3.4) | 0.81 |
| CBCL externalising T score, mean (SD) | 51 (10) | 50 (10) | 0.69 |
| CBCL internalising T score, median [IQR] | 47 [41–55] | 47 [41–55] | 0.59 |
| Visual impairment, n (%) | |||
| None | 213 (90.6) | 166 (86.0) | 0.25 |
| Mild impairment | 19 (8.1) | 25 (13.0) | |
| Limited vision | 3 (1.3) | 2 (1.0) | |
| Blind | 0 (0) | 0 (0) | |
| Hearing loss, n (%) | |||
| None | 229 (98.3) | 185 (96.4) | |
| Mild hearing loss | 2 (0.9) | 3 (1.6) | 0.23 |
| Abnormal, neurosensory hearing loss | 0 (0) | 3 (1.6) | |
| Deaf | 2 (0.9) | 1 (0.5) | |
| Cerebral palsy GMFCS, n (%) | |||
| None | 200 (84.7) | 190 (88.0) | 0.73 |
| Level 1 | 30 (12.7) | 21 (9.7) | |
| Level 2 | 4 (1.7) | 4 (1.9) | |
| Level 3 | 2 (0.8) | 1 (0.5) | |
| Level 4 | 0 (0) | 0 (0) | |
| Level 5 | 0 (0) | 0 (0) | |
| Readmissions until follow-up, n (%) | |||
| None | 130 (57.0) | 149 (69.3) | |
| 1–3 | 83 (36.4) | 50 (23.3) | 0.01 |
| > 3 | 15 (6.6) | 17 (7.4) | |
AOC automated oxygen control, NDI neurodevelopmental impairment, BSID Bayley Scales of Infant and Toddler Development, CBCL Child Behaviour Checklist, GMFCS Gross Motor Function Classification System
aStatistical analysis with independent T-test, χ2, Fishers’ exact, or nonparametric Mann–Whitney U test as appropriate