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. 2023 May 8;13:7431. doi: 10.1038/s41598-023-34447-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Delirium-associated plasma proteins in middle-aged patients. (A) Venn diagrams illustrate the plasma proteins significantly associated with postoperative delirium preoperatively (N = 18, blue), postoperatively (N = 17, pink), or differentially (N = 12, purple). (B–D) Forest plots for delirium-associated plasma proteins preoperatively, postoperatively, and by pre- to postoperative change. * denotes statistically significant proteins within each plot.