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. 2023 May 8;9:151. doi: 10.1038/s41420-023-01449-3

Fig. 5. Repression of m6A activation inhibited N-myc expression in MYCN-amplified NB cells.

Fig. 5

A qRT-PCR analysis of the expression level of METTL3 mRNA in SK-N-BE(2) (n = 3); B qRT-PCR analysis of the expression level of MYCN mRNA in SK-N-BE(2) (n = 3); C qRT-PCR analysis of the expression level of METTL3 mRNA in BE(2)-C (n = 3); D qRT-PCR analysis of the expression level of MYCN mRNA in BE(2)-C (n = 3); E RNA-FISH and immunofluorescence analysis of the expression level of MYCN mRNA and METTL3 in SK-N-BE(2) (Green: MYCN mRNA; Red: METTL3 protein; Blue: DAPI); F RNA-FISH and immunofluorescence analysis of the expression level of MYCN mRNA and METTL3 in BE(2)-C (Green: MYCN mRNA; Red: METTL3 protein; Blue: DAPI).