Table 2.

Antiproliferative activity of spirooxindole derivatives against normal PBL activated with PHA and recombinant IL-2.

Normal PBL	8h	8m	8k	8j
PBL A	53.6 ± 2.1a	48.8 ± 4.9	49.8 ± 3.2	54.0 ± 2.5
PBL B	57.4 ± 5.5	36.1 ± 14.7	55.3 ± 1.4	55.0 ± 3.3
PBL C	65.8 ± 23.2	68.1 ± 23.8	50.9 ± 1.2	61.2 ± 19.7

^aData representing the mean ± SD of 4–6 IC₅₀ values (μM) obtained by the MTT assay.