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. 2023 Apr 12;13(5):3150–3160. doi: 10.21037/qims-22-1035

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2023 Quantitative Imaging in Medicine and Surgery. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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A 42-year-old male patient was intravenously injected with 3.0 mL of SonoVue^® to discriminate malignant thyroid nodules. The patient presented with mild abdominal discomfort after 32 minutes of CEUS. (A) At the same time, scattered tiny hyperechoic spots were detected in the liver. (B) Flowing hyperechoic spots were observed in the portal vein (arrows) (C) After 2 hours of SonoVue^® injection, the patient’s abdominal discomfort was relieved, and the hyperechoic areas in the liver almost disappeared. (D) No hyperechoic spots were found in the portal vein (arrows). CEUS, contrast-enhanced ultrasound.