Table 2.
Angiographic, Procedural, and IVUS Characteristics in the Core Angiographic and IVUS Laboratory in the OPTIVUS Study (per Lesion Basis, Number of Target Lesions = 2,595)
| Angiographic and procedural characteristics | |
| Number of lesions with angiographic evaluation in the core angiographic laboratory | 2,299 |
| Preprocedure | |
| Lesion length, mm | 23.5 ± 13.7 (n = 2,072) |
| Reference vessel diameter, mm | 2.6 ± 0.6 (n = 2,295) |
| Minimum lumen diameter, mm | 0.8 ± 0.4 (n = 2,296) |
| Percent diameter stenosis, % | 68.7 ± 14.1 (n = 2,296) |
| Thrombus | 53/2,297 (2.3) |
| Total occlusion | 174/2,297 (7.6) |
| In-stent restenosis | 81/2,297 (3.5) |
| Bifurcation | 1,092/2,297 (47.5) |
| Moderate or severe calcification | 722/2,297 (31.4) |
| Index procedure | |
| Invasive FFR or iFR use | 413/2,595 (15.9) |
| IVUS use | 2,529/2,595 (97.5) |
| Stent use | 2,379/2,595 (91.7) |
| PCI procedure successa | 2,571/2,595 (99.1) |
| Number of stents used per lesion | 1.0 (1.0-1.0) (n = 2,377) |
| Stent length per lesion, mm | 34.4 ± 18.5 (n = 2,377) |
| Minimum stent diameter, mm | 2.5 (2.5-3.0) (n = 2,377) |
| Cutting or scoring balloon use | 883/2,595 (34.0) |
| Rotational atherectomy use | 171/2,595 (6.6) |
| Orbital atherectomy use | 42/2,595 (1.6) |
| Direct stenting | 183/2,377 (7.7) |
| Maximum stent inflation pressure, atm | 12.7 ± 3.1 (n = 2,372) |
| Post-dilatation | 1,838/2,377 (77.3) |
| Maximum balloon size, mm | 3.2 ± 0.6 (n = 1,838) |
| Maximum balloon inflation pressure, atm | 18.0 ± 4.3 (n = 1,834) |
| Postprocedure | |
| Minimum lumen diameter, mm | |
| In-stent | 2.5 ± 0.5 (n = 2,299) |
| In-segment | 2.2 ± 0.6 (n = 2,299) |
| Percent diameter stenosis, % | |
| In-stent | 14.4 ± 6.7 (n = 2,299) |
| In-segment | 23.7 ± 10.0 (n = 2,299) |
| Acute gain, mm | |
| In-stent | 1.7 ± 0.5 (n = 2,296) |
| In-segment | 1.4 ± 0.6 (n = 2,296) |
| Procedural complications | 75/2,595 (2.9) |
| Side branch occlusion (post TIMI flow grade ≤2) | 23/2,595 (0.9) |
| Slow flow | 36/2,595 (1.4) |
| Acute occlusion | 6/2,595 (0.2) |
| Perforation | 13/2,595 (0.5) |
| Cardiac tamponade | 0/2,595 (0) |
| Stent dislodgement | 1/2,595 (0) |
| Stent thrombosis | 0/2,595 (0) |
| IVUS analysis postprocedureb | |
| Number of lesions with IVUS evaluation in the core IVUS laboratory | 2,046 |
| Proximal reference vessel area, mm2 | 16.1 ± 5.6 (n = 1,684) |
| Proximal reference lumen area, mm2 | 8.3 ± 3.3 (n = 2,046) |
| Minimum stent area, mm2 | 5.7 ± 2.0 (n = 2,046) |
| Distal reference vessel area, mm2 | 9.8 ± 5.1 (n = 1,974) |
| Distal reference lumen area, mm2 | 5.8 ± 2.6 (n = 2,046) |
| Thrombus or protrusion | 261/2,046 (12.8) |
| Incomplete stent appositionc | 745/2,046 (36.4) |
| Dissection | 96/2,046 (4.7) |
| Meeting OPTIVUS criteria | 1,246/2,044 (61.0) |
| Stent length ≥28 mm | 664/1,228 (54.1) |
| Stent length <28 mm | 582/816 (71.3) |
Values are mean ± SD, n/N (%), or median (IQR).
Abbreviations as in Table 1.
a
PCI procedure success was defined as successful dilatation of target lesion with residual diameter stenosis <50%.
b
IVUS analyses were to be performed in all target lesions with stenting.
c
Incomplete stent apposition was defined as the presence of blood flow between stent struts and vessel wall.