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. 2023 Apr 18;3(2):169–184. doi: 10.1016/j.jacasi.2023.01.004

Table 4.

Ongoing Studies for Evaluating the Prevalence, Prognosis, and Management of INOCA

Diagnosis Diagnosis Diagnosis
INOCAIT (NCT05164640) Prospective registry Prevalence, proportion of endotypes, and prognosis of INOCA
DISCOVER INOCA (NCT05288361) Prospective registry Prevalence, proportion of endotypes, and prognosis of INOCA
CorCTCA (NCT03477890) Randomized controlled trial Impact of invasive diagnostic tests for INOCA in classifying and managing INOCA patients
iCorMicA (NCT04674449) Randomized controlled trial Benefit of stratified management of INOCA based on invasive tests
WARRIOR (NCT03417388) Randomized controlled trial Prognostic impact of intensive statin/ACE inhibitor/ARB treatment in INOCA patients
PRIZE (NCT04097314) Randomized controlled trial Antianginal effect of zibotentan in patients with coronary slow flow phenomenon

CorCTCA = Coronary Microvascular Function and CT Coronary Angiography; DISCOVER INOCA = Determining the Cause of Coronary Vasomotor Disorders in Patients With Ischemia and No Obstructive Coronary Artery Disease; iCorMicA = International Study of Coronary Microvascular Angina; INOCAIT = Ischemia in Patients With Non-obstructive Disease [INOCA] in Italy INOCA IT Multicenter Registry; PRIZE = Precision Medicine With Zibotentan in Microvascular Angina; WARRIOR = Women’s Ischemia Trial to Reduce Events in Non-Obstructive CAD; other abbreviations as in Table 3.