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ALKBH5 inhibition promotes therapeutic effects of chemotherapeutic drugs on neuroblastoma cells. (A,B) SK-N-BE(2) (A) and SK-N-SH (B) neuroblastoma cell lines with ALKBH5 knockdown were significantly more sensitive to low doses of carboplatin compared to controls; (C,D) SK-N-BE(2) (C) and SK-N-SH (D) cell lines with ALKBH5 knockdown were significantly more sensitive to low doses of etoposide compared to control. *, P<0.05; **, P<0.01; ****, P<0.0001.
