Table 3:
Postprocedural outcomes.
| All(2010–2019)n = 489 | Group 1 (2010–2015) n = 132 |
Group 2 (2016–2017) n = 155 |
Group 3 (2018–2019) n = 202 |
p value | |
|---|---|---|---|---|---|
| Postprocedural outcomes | |||||
| In-hospital mortality - n (%) | 26 (5.3 %) | 12 (9.1 %) | 9 (5.8 %) | 5 (2.5 %) | 0.029 |
| Myocardial infarction - n (%) | 2 (0.4 %) | 2 (1.5 %) | 0 (0.0 %) | 0 (0.0 %) | 0.066 |
| Neurological complications (all) - n (%) | 11 (2.2 %) | 2 (1.5 %) | 3 (1.9 %) | 6 (3.0 %) | 0.647 |
| - Stroke - n (%) | 9 (1.8 %) | 2 (1.5 %) | 2 (1.3 %) | 5 (2.5 %) | 0.675 |
| - TIA - n (%) | 2 (0.4 %) | 0 (0.0 %) | 1 (0.6 %) | 1 (0.5 %) | 0.673 |
| Bleeding complications (all) - n (%) | 53 (10.8 %) | 19 (14.4 %) | 18 (11.6 %) | 16 (7.9 %) | 0.165 |
| - Life-threatening bleeding - n (%) | 18 (3.7 %) | 5 (3.8 %) | 6 (3.9 %) | 7 (3.5 %) | 0.977 |
| - Major bleeding - n (%) | 12 (2.5 %) | 3 (2.3 %) | 5 (3.2 %) | 4 (2.0 %) | 0.743 |
| - Minor bleeding - n (%) | 23 (4.7 %) | 11 (8.3 %) | 7 (4.5 %) | 5 (2.5 %) | 0.047 |
| - Blood transfusion - n (%) | 121 (24.7 %) | 47 (35.6 %) | 40 (25.8 %) | 34 (16.8 %) | < 0.001 |
| - Transfusion of thrombocyte concentrates - n (%) | 21 (4.3 %) | 7 (5.3 %) | 7 (4.5 %) | 7 (3.5 %) | 0.711 |
| - Transfusion of fresh frozen plasma - n (%) | 20 (4.1 %) | 7 (5.3 %) | 8 (5.2 %) | 5 (2.5 %) | 0.318 |
| Acute Kidney Injury (AKIN) (all) - n (%) | 183 (37.4 %) | 71 (53.8 %) | 53 (34.2 %) | 59 (29.2 %) | < 0.001 |
| - AKIN I - n (%) | 152 (31.1 %) | 57 (43.2 %) | 48 (31.0 %) | 47 (23.3 %) | 0.001 |
| - AKIN II - n (%) | 3 (0.6 %) | 0 (0.0 %) | 0 (0.0 %) | 3 (1.5 %) | 0.117 |
| - AKIN III - n (%) | 28 (5.7 %) | 14 (10.6 %) | 5 (3.2 %) | 9 (4.5 %) | 0.016 |
| - Dialysis after TAVI (all) - n (%) | 24 (4.9 %) | 11 (8.3 %) | 4 (2.6 %) | 9 (4.5 %) | 0.074 |
| - Acute dialysis after TAVI - n (%) | 13 (2.7 %) | 6 (4.5 %) | 4 (2.6 %) | 3 (1.5 %) | 0.235 |
| Vascular complications (all) – n (%) | 66 (13.5 %) | 20 (15.2 %) | 20 (12.9 %) | 26 (12.9 %) | 0.809 |
| - Major vascular complication - n (%) | 23 (4.7 %) | 7 (5.3 %) | 6 (3.9 %) | 10 (5.0 %) | 0.83 |
| - Minor vascular complication - n (%) | 40 (8.2 %) | 12 (9.1 %) | 12 (7.7 %) | 16 (7.9 %) | 0.903 |
| - Percutaneous closure device failure- n (%) | 4 (0.8 %) | 1 (0.8 %) | 2 (1.3 %) | 1 (0.5 %) | 0.708 |
| Conduction disturbances andarrhythmias (all) - n (%) | 242 (49.5 %) | 64 (48.5 %) | 77 (49.7 %) | 101 (50.0 %) | 0.962 |
| - New AV block 1 - n (%) | 48 (9.8 %) | 11 (8.3 %) | 16 (10.3 %) | 21 (10.4 %) | 0.799 |
| - New AV block 2 - n (%) | 7 (1.4 %) | 1 (0.8 %) | 2 (1.3 %) | 4 (2.0 %) | 0.645 |
| - New AV block 3 - n (%) | 35 (7.2 %) | 5 (3.8 %) | 6 (3.9 %) | 24 (11.9 %) | 0.003 |
| - New LBBB - n (%) | 109 (22.3 %) | 24 (18.2 %) | 36 (23.2 %) | 49 (24.3 %) | 0.403 |
| - New RBBB - n (%) | 6 (1.2 %) | 2 (1.5 %) | 1 (0.6 %) | 3 (1.5 %) | 0.728 |
| - New LAFB - n (%) | 34 (7.0 %) | 17 (12.9 %) | 11 (7.1 %) | 6 (3.0 %) | 0.002 |
| - New onset atrial fibrillation - n (%) | 24 (4.9 %) | 4 (3.0 %) | 7 (4.5 %) | 13 (6.4 %) | 0.357 |
| - Hemodynamic relevant arrhythmia-n (%) | 29 (5.9 %) | 6 (4.5 %) | 16 (10.3 %) | 7 (3.5 %) | 0.018 |
| - New permanent pacemaker implantation - n (%) | 73 (14.9 %) | 10 (7.6 %) | 17 (11.0 %) | 46 (22.8 %) | < 0.001 |
| Valve malposition (all) - n (%) | 5 (1.0 %) | 0 (0.0 %) | 3 (1.9 %) | 2 (1.0 %) | 0.267 |
| - Valve migration - n (%) | 1 (0.2 %) | 0 (0.0 %) | 1 (0.6 %) | 0 (0.0 %) | 0.34 |
| - Valve embolization - n (%) | 4 (0.8 %) | 0 (0.0 %) | 2 (1.3 %) | 2 (1.0 %) | 0.452 |
| - Ectopic valve deployment - n (%) | 0 (0.0 %) | 0 (0.0 %) | 0 (0.0 %) | 0 (0.0 %) | |
| Other Complications | |||||
| - Ventricle injury - n (%) | 6 (1.2 %) | 2 (1.5 %) | 2 (1.3 %) | 2 (1.0 %) | 0.909 |
| - Pericardial tamponade - n (%) | 8 (1.6 %) | 2 (1.5 %) | 4 (2.6 %) | 2 (1.0 %) | 0.492 |
| - Sepsis - n (%) | 5 (1.0 %) | 3 (2.3 %) | 1 (0.7 %) | 1 (0.5 %) | 0.252 |
| - Endocarditis - n (%) | 1 (0.2 %) | 0 (0.0 %) | 1 (0.7 %) | 0 (0.0 %) | 0.328 |
| Paravalvular insufficiency - n (%) | 0.401 | ||||
| - Grade 1 | 127 (26.0 %) | 30 (22.7 %) | 38 (24.5 %) | 59 (29.2 %) | |
| - Grade 2 | 23 (4.7 %) | 4 (3.0 %) | 7 (4.5 %) | 12 (5.9 %) | |
| - Grade 3 | 0 (0.0 %) | 0 (0.0 %) | 0 (0.0 %) | 0 (0.0 %) | |
| Hospitalization after TAVI (days) | |||||
| - Mean (± SD) | 11.1 (± 10.2) | 11.8 (± 6.4) | 11.5 (± 14.2) | 10.4 (± 8.4) | < 0.001 |
| - Median (IQR) | 8.0 (6.0) | 9.0 (8.0) | 8.0 (6.0) | 8.0 (6.0) | |
| Stay at ICU und IMC after TAVI (days) | |||||
| - Mean (± SD) | 4.4 (± 6.1) | 4.8 (± 5.0) | 4.6 (± 4.1) | 2.6 (± 7.1) | 0.001 |
| - Median (IQR) | 3.0 (3.0) | 3.0 (5.0) | 3.0 (4.0) | 2.0 (2.0) | |
Abbreviations: AV = Atrioventricular; ICU = Intensive Care Unit; IMC = Intermediate Care Unit; IQR = Interquartile Range; LAFB = Left Anterior Fascicular Block; LBBB = Left Bundle Branch Block; RBBB = Right Bundle Branch Block; SD = Standard Deviation; TIA = Transient Ischemic Attack.