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. 2023 May 9;2023(5):CD013350. doi: 10.1002/14651858.CD013350.pub2

Jirapramukpitak 2020.

Study characteristics
Methods Study design: randomized controlled trial
Country: Thailand
Setting: community/home visits
Eligibility criteria: adults with alcohol dependence who have not engaged in alcohol treatment in the past 3 months
Duration of follow‐up: 16 weeks
Informed consent: all participants provided informed consent
Ethical approval: study procedures were approved by the ethics committee of Thammasat University
Participants Sample size: 161 (80 intervention, 81 control)
Description of the target population: People with alcohol dependence in the community
Age: 50.1 years (SD = 11.5)
Sex: 75.2% male
Race/Ethnicity: not reported
Marital status: 59.6% married
Harmful alcohol use (baseline): 41% had a positive breathalyzer sample
Co‐occurring disorders: 3.7% had a comorbid psychiatric illness
Interventions Type: non‐pharmacologic
Description: home visits with contingency management (2 doses: high value prizes, low value prizes)
Duration and frequency: 40 home visits (10‐15 minutes each) over 12 weeks
Delivery and provider: Village health volunteers
Comparison group: 40 home visits focused on giving advice on alcohol use
Outcomes Primary outcome(s): abstinence
Primary outcome measurement tool(s): breathalyzer
Secondary outcome(s): current psychological distress
Secondary outcome measurement tool(s): Addiction Severity Index
Time points: 2, 3, 8, 12, 16 weeks
Notes Study funding and conflicts of interest: Thai Health Promotion Foundation
Linked study records: none
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote "The unit of randomization was the individual participant. Random‐ ization of participants to different arms was carried out at the Coor‐ dinating Centre in the Mental Health Clinic of Thammasat University Hospital using a standard randomization table (Pocock, 1983). Strat‐ ified randomization procedures were followed to randomly assign participants to HV, CM‐L and CM‐H arms in a 2:1:1 ratio. The variables on which groups were stratified included: age (greater than 50), gender and current psychological distress." Pg. 173
Allocation concealment (selection bias) Unclear risk Quote "In order to keep both the HV and CM groups of similar size, random allocation was done in blocks of 4." Pg. 173
Blinding of participants and personnel (performance bias)
All outcomes High risk Not able to mask providers or participants given nature of the intervention
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Not reported
Incomplete outcome data (attrition bias)
All outcomes Low risk Low attrition and levels of missing data
Selective reporting (reporting bias) Unclear risk Not reported