Vlasova 2011.

Study characteristics
Methods	Study design: Randomized controlled trial Country: Ukraine Setting: Alcohol and drug treatment center Eligibility criteria: Included were new admissions 19 years and above to the treatment center with a primary diagnosis of alcohol dependence and willing to participate in 4 months of an outpatient treatment program following completion of 30+ days of inpatient treatment. Excluded were people with severe psychiatric disorder or organic brain syndrome preventing their ability to provide informed consent Duration of follow‐up: 4 months Informed consent: All participants provided written informed consent Ethical approvals: University of Alabama Birmingham Instutional Review Board, Vinnitsya National Medical University‐Pirogov Ethics Board
Participants	Sample size: 68 (34 intervention, 34 control) Description of the target population: Patients admitted to inpatient treatment for alcohol use disorder Age: 37.2 years (SD=11.8) Sex: 14.7% female Race/Ethnicity: Not reported Marital status: Not reported Harmful alcohol use (baseline): 100% reported past 30‐day alcohol use and met criteria for alcohol dependence Co‐occurring disorders: Not reported
Interventions	Type: Non‐pharmacologic Description: Inpatient treatment followed by intensive outpatient treatment including individual sessions, 12‐step facilitation, weekly aftercare, and sponsors group Duration and frequency: 30+ day inpatient medical treatment, 2 months of 12‐step oriented day treatment (8 hours per day), 1 month of aftercare (2 hours per week), and 1 month of sponsors group (2 hours per week) Delivery and provider: Physicians, social workers, psychologists, nurses Comparison group: Usual care (inpatient treatment) involving medical detoxification, acute medical care, primary medical care, and some counseling and social services for 30 days provided by physicians, social workers, psychologists, and nurses
Outcomes	Primary outcome(s): Alcohol consumption (days) Primary outcome measurement tool(s): Form 90 Secondary outcome(s): Drinks per day, Heavy drinking days, Alcohol‐related consequences, Mental health, Depression Secondary outcome measurement tool(s): Form 90, Drinker Inventory of Consequences, Short Form‐36 Version 2 Health Survey, Beck Depression Inventory II Time points: 2, 4 months
Notes	Study funding and conflicts of interest: National Institute of Health and Fogarty International Center Linked study records: Vlasova 2005
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"Participants were recruited from interested alcohol‐dependent patients admitted to the RND early in treatment. They were assessed and randomly assigned to 1 of the 2 intervention groups." Pg. 8
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants and personnel (performance bias) All outcomes	High risk	Participants and personnel cannot be blinded for this type of intervention
Blinding of outcome assessment (detection bias) All outcomes	High risk	Outcomes reported by participant not blind to intervention
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Not described
Selective reporting (reporting bias)	Unclear risk	Protocol not available