Table 1.

Common obstetric medications and treatments

Condition	Diagnostic assessment	Medication or treatment
PPH	Fundal check for uterine tone Rapid bedside ultrasound or pelvic exam for retained products Laboratory evaluation for DIC or coagulation defect	Atony: Uterotonics: Oxytocin, misoprostol, methergine, carboprost Antifibrinolytics: TXA 1 g IV Uterine tamponade: Balloon or vacuum device Surgical intervention
Antepartum hemorrhage	Evaluation for abnormal placentation Clinical signs of placental abruption (painful contractions, vaginal bleeding, nonreassuring fetal heart tracing) Evaluation of Rh status	Consideration for delivery Rhogam administration pending clinical scenario
Preeclampsia	Evaluation of blood pressure (elevated 140/90, severe 160/110) Evaluation for proteinuria Evaluation for thrombocytopenia, transaminitis, renal insufficiency, pulmonary edema, or clinical signs	Treatment of severe blood pressures within 15 min: IV labetalol, hydralazine, PO nifedipine, or nicardipine or sodium nitroprusside Prevention of seizures
Eclampsia	New-onset seizures in a patient with preeclampsia Usually self-limiting	Magnesium 4 g or 6g IV loading dose with 2 g/h continuous to prevent further seizures
Amniotic fluid embolus	Cardiorespiratory arrest or compromise and DIC at time of labor	Supportive ACLS, with MTP and fluid support A OK regimen (anecdotal): 1 mg atropine, 8 mg ondansetron, 15 mg ketorolac
Sepsis	Evaluation for cause, including endometritis or chorioamnionitis on differential	Surviving sepsis treatment Ampicillin/gentamicin for chorioamnionitis Ampicillin/gentamicin/metronidazole for endometritis

DIC: Disseminated intravascular coagulation, TXA: Tranexamic acid, MTP: Massive transfusion protocol, PPH: Postpartum hemorrhage, IV: Intravenous, ACLS: Advanced cardiac life support, PO: Per os