Table 3.

Clinical variables at time of confirmatory biopsy associated with subsequent AS progression to GG ≥2

	Multivariate
Variables	HR	p Value
Age	1.03 (0.99–1.08)	0.15
PSA	0.96 (0.86–1.08)	0.49
PSAD	2.21 (1.41–3.48)	<0.001 *
Pos cores on systematic biopsy	0.94 (0.75–1.18)	0.61
Bilat disease	3.06 (1.31–7.13)	0.009 *

^*Values in bold indicate statistical significance (p <0.05).