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. Author manuscript; available in PMC: 2024 Apr 6.
Published in final edited form as: Structure. 2023 Mar 3;31(4):385–394.e4. doi: 10.1016/j.str.2023.02.005

Figure 6. Structural Comparison of the T- and F-pilus.

Figure 6.

Helical cross-sections showing organization of pilins and phospholipids in (A) F-pilus (PDB ID: 5LEG) and (B) T-pilus. The T-pilus adopts a denser structure with narrower lumen. The F-pilus lumen is moderately negatively charged (reproduced from Costa et al., 2016), whereas T-pilus lumen is neutral. (C) Structural overlay and secondary structure annotation of T-pilus VirB2 (yellow) and F-pilus TraA (purple). Phospholipids from equivalent positions in the helical packing are displayed.